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The prosperous and overweight burgher with gout is a classical European image of the 19th century, but in reality gout affects those of all economic classes
Nature 519 , 477481 (2015)
Hillis, W., Inoue, T
Non-senescent cells do not rely on this interaction, so they are not affected
The activation of HSCs is due to several intracellular and extracellular events and signals, including oxidative stress and transforming growth factor Smad3 pathway activation
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