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The study found that early and rapid improvements in markers of liver injury and lipid abnormalities with sebelipase alfa were sustained, with no progression of liver disease, for up to 5 years (45)
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It is not approved for human or animal administration and must not be used in foods, supplements, pharmaceuticals, or cosmetics
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To be eligible, studies had to report at least one exercise-related outcome, such as aerobic capacity, muscle strength, enzymatic or mitochondrial activity, or biochemical indices
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