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Here, we loaded fluorescent dyes DiL and DiD into BA/Res@NP and injected them together with the small-molecule luminescent probe luminol, employing the BRET-FRET effect between luminol and NP to transfer the light emitted by luminol to the NIR region

McKee and Ebert 1996)

At a certain blood concentration of cortisol this protection is ostensibly achieved and the cortisol exerts negative feedback to the hypothalamic release of CRF and the pituitary release of ACTH (negative feedback)

Heat stress was applied to the Heat Control, Niacin 1, and Niacin 2 groups by exposing the animals to 36 2 C and 55% relative humidity for 4 h daily (10:0014:00) over 30 consecutive days 71 , following methodologies validated in rodent and rat studies assessing testicular ischemia-reperfusion and reproductive stress models 25,50,72,73

Although composite models better recapitulate disease progression, their complexity, long duration, and high cost severely restrict their use as mainstream platforms for high-throughput screening and mechanistic studies

While the exact cause of dystonia is still unknown, research has identified several risk factors that may contribute to the development of this neurological disorder