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reported that FBXL4 deficiency could result in severe multi-system diseases, including lactic acidosis, cystic white matter disease, cardiomyopathy, arrhythmia, and immunodeficiency (141)

Updated June 2026 Medically reviewed 12 min read Important: This guide is for information only and does not replace medical advice

Histone H2B deacylation selectivity: exploring chromatins dark matter with an engineered sortase

Heparan sulphate proteoglycans fine-tune mammalian physiology

USA 105 , 1177211777 (2008)

the PFC follows an inverted-U where more is not better
