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Acute injection with 12,13-DiHOME affected the cardiomyocytes by increasing mitochondrial respiration resulting in increased cardiac hemodynamics

In vitro models for the bloodbrain barrier

55 Although adiponectin does not seem to cross the blood-brain barrier, 56,57 the ARC 58 and the area postrema 59 respond to adiponectin, suggesting that these cells could be involved in relaying the signal to other brain regions