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However, in rare casessuch as patients with kidney disease or specific hereditary disorders related to vitamin B12 metabolismhigh doses or inappropriate use could potentially cause complications

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Kasumov, T

The crucial function of B12 in sleep latency is reinforced by a previous study that examined the impact of vitamin B12 supplementation on the sleepwake cycle of individuals with delayed sleep phase syndrome, showing a significant temporary improvement in the supplemented group [26]

2004;32(Pt 5):8126

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