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10.1097/OPX.0b013e318194e767

L-propionylcarnitine effect on postexercise and postischemic hyperemia in patients affected by peripheral vascular disease

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[DOI] [PubMed] [Google Scholar] 77.Takashima H., Maruyama T., Abe M

The presence of cholesterol stones may indicate increased bile cholesterol due to hepatic secretions, quick changes in the bile's cholesterol phase, or decreased motility combined with excessive secretion and accumulation of mucin in the gallbladder causing inflammation[3,10]

That means clinicians and users rely heavily on mechanistic insight and clinical experience to manage the issue