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The observation that the loss of FH, a bona fide tumour suppressor gene 22 , could lead to senescence, although counterintuitive, suggests that the role of FH in tumorigenesis is complex and might involve secondary oncogenic alterations to overcome senescence

The formation of DTP cells not only showcases redox-regulated mechanisms but also reveals their resistance to pro-ROS drugs

It can treat diseases caused by gene abnormalities by introducing normal genes to replace missing or abnormal mutated genes, or inhibiting the function of abnormal endogenous genes

Bioinformatics 40 , btae342 (2024)

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This family includes a large and heterogeneous group of membrane channels, non-selectively permeable to cations
