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metformin is especially effective in individuals under 60 with a BMI of 35 or higher []

Neurochem Int (2018) 120:14963

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found that a four-week treatment combining antibiotics and probiotics enhanced neurological symptoms and sleep quality, though it did not alleviate fatigue symptoms linked to ME/CFS [44]

Extended life-span and stress resistance in the Drosophila mutant methuselah

An important process is nitric oxide inactivation through its reaction with superoxide radicals, which results in the formation of peroxynitrite ONOO
