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For example, a 2005 study found that NAC administration failed to raise glutathione levels in rats,36 and a 2022 study on mice suggested that it may promote the metastatic spread of certain cancers.37 While its true that animal studies don't directly translate to human outcomes, they're still important to consider when choosing a supplement meant to support your health and wellness

While many of these treatments induced both GCLC and GCLM expression, selective transcriptional induction of only GCLC occurred when cultured rat hepatocytes were treated with insulin or hydrocortisone [6466]

( 6 ) Here are 10 ways to naturally increase your glutathione levels: Eat more sulfur-rich foods Up your vitamin C intake Add selenium-rich foods to your diet Supplement with whey protein Get more sleep Try adding turmeric into your diet Exercise regularly Cut back on the alcohol Meditation Breathing techniques that relieve stress Best Foods Naturally Rich in Glutathione Despite the fact that glutathione is produced by the body it can be beneficial to consume dietary sources that are particularly abundant in this powerful antioxidant such as: Unprocessed meat Garlic Broccoli Asparagus Spinach Avocado Okra But it's important to note that while all of these foods are a great natural source of glutathione, dietary glutathione is poorly absorbed by the body

Glutathione Benefits: Evidence, Use & Safety Glutathione Benefits: Evidence, Use & Safety (2025) Glutathione (GSH) is often hailed as the "master antioxidant." But does it live up to the hype