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doi: 10.1038/nrdp.2017.40

Vitamin B12 shot side effects Most people tolerate vitamin B12 injections well, but possible side effects include: Mild: soreness or redness at injection site, mild diarrhea, nausea, headache, itching Rare but serious: allergic reactions (rash, swelling, difficulty breathing), low potassium (hypokalemia), dizziness or heart rate changes Get emergency medical help if you have signs of an allergic reaction to Vitamin B12: hives

Start: 200 mcg once daily Increase: Add ~200 mcg every 2 weeks as tolerated Target Range: 400600 mcg once daily Frequency: Once daily Cycle Length: Typically 812 weeks Timing: Any consistent daily time