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After 3 months, volanesorsen markedly lowered plasma apoC-III ( 76%) and triglyceride ( 71%) concentrations, but increased plasma LDL cholesterol (+ 96%), which were sustained over 6 months of treatment
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Cell 119:285298 Li YP, Chen Y, John J, Moylan J, Jin B, Mann DL, Reid MB (2005) TNF-alpha acts via p38 MAPK to stimulate expression of the ubiquitin ligase atrogin1/MAFbx in skeletal muscle
And guessing doesn't produce citations
