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Inhibition of phosphoglycerate dehydrogenase attenuates bleomycin-induced pulmonary fibrosis

* Correspondence: Qinming Yu, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Upon determining the optimal pH for each enzyme, velocities were determined for multiple substrate and enzyme concentrations at each enzymes optimal pH, and the Michaelis-Menten kinetics module in SigmaPlot was used to calculate K m , k cat , and catalytic efficiency

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Heat stress prevents the decrease in succinate dehydrogenase activity in the extensor digitorum longus of streptozotocin-induced diabetic rats