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However, over time, the accumulation of senescent cells in tissues leads to a decline in cellular function and the development of a range of age-related conditions, including cardiovascular diseases, neurodegenerative disorders, and cancers.1,2 The presence of these cells is often accompanied by the senescence-associated secretory phenotype (SASP), a pro-inflammatory state that can exacerbate tissue dysfunction and promote chronic disease progression

10.1074/jbc.M609582200 J Biol Chem

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