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Indeed, chronic alcoholism and nicotine consumption are independent risk factors for pancreatitis, and both inhibit pancreatic thiamine uptake via downregulation of thiamine transporters (90)
(2023) 103:adv11643
[4] Frye RE, Slattery J, Delhey L, Furgerson B, Strickland T, Tippett M, Sailey A, Wynne R, Rose S, Melnyk S, Jill James S, Sequeira JM, Quadros EV
But these findings have not been confirmed in humans
[12] reported that GHK increased the expression of p63 and PCNA, markers of stemness and cellular proliferation, in a keratinocyte model
