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Right after you receive the shot, however, you may see some slight skin irritation at the injection site
Ontario Health Technology Assessment Series 2013;13:124

Bismah Irfan, MD Functional & Integrative Medicine, Houston, TX

The deficiency of B12 is mostly due to inherited defects which result in malabsorption or the impaired transport of the vitamin within the body

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Furthermore, co-administration of arginine with potassium-sparing diuretics (e.g., spironolactone, amiloride) is cautioned, as both can increase serum potassium levels and together may precipitate hyperkalemia (high potassium), which in turn may lead to dangerous heart arrhythmias