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Dietary adjustments often provide significant relief, including eating smaller, more frequent meals rather than large portions, avoiding high-fat or spicy foods that may exacerbate symptoms, and eating slowly to allow for better digestion

Comparative study of therapeutic effects of 20% azelaic acid and hydroquinone 4% cream in the treatment of melasma

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Refrigerate only if you prefer the taste chilled

This situation was first reported in a boy with a deletion of exon 4 of the IGF-I gene (90) resulting in severe fetal and post-natal growth arrest, poor brain development and extreme insulin resistance with compensatory hyperinsulinemia and acanthosis nigricans