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MC4R is activated by -melanocyte stimulating hormone (-MSH), which is primarily produced by pro-opiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus (Krashes et al., 2016)

Den kjemiske sekvensen til Melanotan II er Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-NH2

This mechanism could be an idea for inhibition of CDI, for example, by adding some deoxycholate to antibiotic regimens of infected patients

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The most common issues that affect the radius are fractures, osteoporosis and damage to nerves or muscles around it

doi: 10.1054/plef.2001.0281