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Both the mRNA and protein levels of PSAT1 in ER-positive primary tumors are associated with poor clinical outcomes following tamoxifen treatment, suggesting that combination with a regimen targeting PSAT1 might enable therapeutic efficacy in this subset of breast cancer 26

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[DOI] [PMC free article] [PubMed] [Google Scholar] 183.Tate S.S., Meister A

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aim is to provide at least 120 - 140 meg / litre of plasma over at least 12 hrs, preferably over at least 24 hrs period, more preferably over at least 48 hrs and most preferably over at least 72 hrs