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Parenteral and intranasal cyanocobalamin, vitamin B12 are classified as pregnancy category C

Appropriate caution should be exercised while treating severe megaloblastic anemia with cyanocobalamin as intense treatment may lead to hypokalemia and sudden death

Researchers should note that AOD-9604 completed Phase II clinical trials under the pharmaceutical development programme of Metabolic Pharmaceuticals before the programme was discontinued

pregnant women often receive IV thiamine if needed (e.g., for hyperemesis) without issue

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