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Steady state (Weeks 38): Continue the same daily dose

[9] Concomitant administration of large calcium supplements, thiazide diuretics, or aluminium-containing phosphate binders can potentiate vitamin D-mediated increases in serum calcium or phosphate, demanding periodic laboratory monitoring and dosage adjustments to avert nephrolithiasis or ectopic calcification

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Mental illnesses including depression and seasonal affective disorder often correlate with suboptimal B12 levels , particularly during winter months when natural Vitamin D3 synthesis decreases

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Gastrointestinal absorption of vitamin B 12 depends on the presence of sufficient intrinsic factor and calcium ions