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Whilst evidence of the role TRPM3 ion channel dysfunction in NK cells plays in ME/CFS pathophysiology has the potential to demonstrate a biological (as opposed to psychological) etiology, there are presently limitations to applying this as a potential diagnostic tool

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For ADHD, this might include creating organized spaces with clear systems, minimizing distractions in work areas, incorporating movement opportunities, and using visual reminders and organizational tools

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Vertical bands involving underlying muscle (platysmal bands) respond less to topical treatment but may still show some improvement in overlying skin texture