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have demonstrated through various studies that while the role of sorbitol in the polyol pathway is still debated, it plays a significant part in triggering diabetes (Singh et al., 2021)

Nutrients 15(17):3821 Laaksonen DE, Niskanen L, Punnonen K, Nyyssonen K, Tuomainen TP, Valkonen VP, Salonen JT (2004) Testosterone and sex hormonebinding globulin predict the metabolic syndrome and diabetes in middle-aged men

For example, some SERMs act as agonists on ERs located in the brain and as antagonists in the uterus and mammary gland [53,54], so their use could represent an advantage

doi: 10.1016/j.freeradbiomed.2021.10.028, 24

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