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Studies have shown that adding n-3 LCPUFA to TB treatment regimens reduced M.tb burden [50], decreased systemic and lung inflammation [51], and enhanced weight in M.tb -infected C3HeB/FeJ mice with a sufficient n-3 LCPUFA status [52]

Int J Microbiol 2015, 376387

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Adenosine A 2A receptor occupancy stimulates collagen expression by hepatic stellate cells via pathways involving protein kinase A, Src, and extracellular signal-regulated kinases 1/2 signaling cascade or p38 mitogen-activated protein kinase signaling pathway

[DOI] [PMC free article] [PubMed] [Google Scholar] 68.Ebrahimi M, Teymouri K, Chen CC, Mohiuddin AG, Pouget JG, Goncalves VF, Tiwari AK, Zai CC, Kennedy JL

Cofactors (e.g., activators and repressors) are key molecules in the determination of downstream responses produced by receptor activation