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Firstly, we observed that metformin was able to partially alleviate OA pain in the monosodium iodoacetate (MIA)-induced mouse model as assessed by animal behavior tests

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These engineering both enriched native soil non-toxigenic indole-3-acetic acid (IAA)-producing Aspergillus flavus and Sphingomonas, boosting rhizospheric IAA accumulation by 15.7 to 23.6-fold