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Pre-publication / mechanism reference

The titration schedule is a maximum framework, not a mandatory escalation

In case the participant had not reached at least the first sleep stage 30 min after the administration of the first drug, the second drug was chosen: the participants who received Dex as the first drug received Mel as the second drug, and those who received Mel as the first drug were given Dex (route of administration was again randomly chosen)

While IV therapy can be extremely beneficial for traumatic brain injury patients, you should be aware of the possible treatment risks

This effect is achieved by promoting GDH1 expression through the downregulation of the epidermal growth factor receptor (EGFR)/MEK/ERK signaling pathway [56]

Firstly, the analysis was conducted on data from all subjects and, secondly, only on data from women of childbearing age (18- to 45-year-old women)