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In contact dermatitis and atopic dermatitis, inhibition of 15-LOX inhibits podosome formation in dendritic cells, downregulates the antigen uptake and cell migration capabilities, and contributes to the alleviation of skin inflammation (Han et al., 2017)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 74.Calabrese E.J., Osakabe N., Di Paola R., Siracusa R., Fusco R., DAmico R., Impellizzeri D., Cuzzocrea S., Fritsch T., Abdelhameed A.S., et al

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The protective effect of luteolin on the depression-related dry eye disorder through Sirt1/NF-B/NLRP3 pathway