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He et al., 2013)

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How do I properly reconstitute peptides without damaging them

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It is generally accepted that NRF2 is sequestered by KEAP1 in the cytoplasm under normal conditions and is released from KEAP1 before translocating into the nucleus under oxidative stress (Figure 1)

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Lyttle MH, Docker MD, Hui HC, Caldwell CG, Aaron DT, Engqvist-Goldstein A, Flatgaard JE and Bauer KE

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