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Valproic acid itself will slow gastric motility, so whole bowel irrigation may be most likely to succeed if initiated immediately following intubation (when drug levels are still relatively low)

Finally, VPA could also exert direct effects on excitable membranes, and alter dopaminergic and serotoninergic neurotransmissions [10]

10.1159/000242999 201 XuB.-t.TengF.-y.WuQ.WanS.-r.LiX.-y.TanX.-z.et al (2022)

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Several studies have also reported that L-carnitine, and particularly ALCAR can protect the developing brain from deleterious effects of exposure to clinically used anesthetic agents [154157]