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Among T1DM patients using KD, episodes of DKA are clearly sporadic (as they are observed in only a small subset of T1DM patients following a ketogenic diet, most likely as a consequence of improper dietary implementation) [19], but nevertheless should be kept in mind

3.3 Mitochondrial integrity Recently, studies have reported that ketone bodies play a role in maintaining mitochondrial integrity in heart disease (Snorek et al., 2012)

10.1007/s11064-016-2099-2 Neurochem Res
Although these results should be confirmed by a large, randomized, experiment to validate a possible therapeutic role, considering the low cost and the good safety profile, L-carnitine therapy could be now deemed as a possible treatment in selected, high-risk patients

In the modified intent-to-treat population (n = 145), the mean ln ratio in PWT was 0.241 for the cilostazol + L-carnitine treatment group versus 0.134 for the cilostazol + placebo treatment group (p = 0.076)

10.1016/j.tips.2009.09.001 5 AimoA.CastiglioneV.VergaroG.PanichellaG.SenniM.LombardiC
