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Magnetic resonance imagingderived proton density fat fraction (MRI-PDFF) quantifies liver fat with high precision, and a relative reduction of at least about 30% is a commonly used response threshold in early-phase studies

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Of adults receiving combination cagrilintide and semaglutide, 71.4% lost at least 10% of their body weight and 53.6% achieved a 15% or higher weight loss at 32 weeks