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Only a small amount in the plasma is free and active, most is bound to globulin or albumin

Additionally, multivitamin supplementation, particularly vitamin B12 (cobalamin), may be beneficial for neuronal protection

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Many studies showed that the intestinal mucosa of IBS patients contains larger numbers of immune cells and evidence of a higher state of activation of the immune system (218)

A cycle of 4-6 weeks is common for noticeable results

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