gst glutathione dissociation constant Glutathione‐S‐transferase‐green fluorescent protein fusion protein reveals slow from high site density beads and measures free GSH - Tessema - 2006 - Cytometry Part A Measurement of apparent dissociation constant

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Current pharmaceutical biotec hnology

For example, resistance to several antimetabolite drugs can result from impaired drug uptake into cells, overproduction or reduced affinity of the drug target, upregulation of alternative metabolic pathways, impaired activation or increased inactivation of the antimetabolite, as well as increased drug (or metabolite) efflux

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[DOI] [PubMed] [Google Scholar] 6.Beggs MR, Alexander RT

It inhibits intracellular iron export by degrading iron transporter proteins ( In addition to regulating ferroptosis by activating inflammation-related signaling pathways, some inflammatory cells are associated with the occurrence and development of ferroptosis in DN