labial melanotic macula macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight ⬆️ in single basal melanocytes; NO nests. More info like this in An oral melanotic macule is
Description
I learned the secrets of the hormone insulin and the lesser-known hormone leptin, that by evolving toward a very low-glycemic, high-fat (not just high-protein) diet, I had re-sensitized my biochemistry to these essential hormones, which turn off severe food cravings
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Always confirm dosing with your vet, particularly if your dog takes heart medication

doi:10.1074/jbc.M205603200

Obesity-linked variants of melanocortin-4 receptor are misfolded in the endoplasmic reticulum and can be rescued to the cell surface by a chemical chaperone
Wulf GG, Wang RY, Andreeff M , Brenner MK, Goodell MA