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Some mechanistic research relies on non-disease-specific models or tumor cell lines, and the applicability of their conclusions in clinical settings of autoimmune diseases remains to be verified

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By isolating the C-terminal fragment responsible for lipolysis and modifying it to improve stability and activity, researchers created a compound that promotes fat loss without affecting glucose metabolism or stimulating tissue growth

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BPC-157 has a large publication count concentrated in tendon, gastrointestinal and angiogenesis models, but the publication count is dominated by a single research group, and the field has been slow to produce independent replication of the largest effect sizes