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ROS exert cellular toxicity by modifying DNA, lipids, and proteins through DNA base oxidation, lipid peroxidation, and protein carbonylation (protein oxidation), respectively 7,8,9

The intricate metabolic microenvironment within the tumor, characterized by nutrient gradients, hypoxia, and interactions with stromal cells, adds another layer of complexity to the design and implementation of glutamine-targeted therapies [40,43,44,45,46]

From the peptide that is found in gastric juices

CALDER, I.C., YONG, A.C., WOODS, R.A., CROWN, C.A., HAM, K.N., & TANGE, J.D

The negative value of G ( 3.15 kJ/mol) revealed that binding process is spontaneous