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In contrast, SOCS3, which has been shown to be increased in DCs by tumor-derived substances, interacts with PKM2, resulting in decreased ATP generation under hypoxic conditions and a profound effect on the function of DCs (61)

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Our findings highlight the critical importance of selective antioxidant gene alteration in increasing enzyme yields and establish the framework for future research into the genetic optimization of microbial strains for increased production of commercially important enzymes

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The location of novel versus familiar object was counterbalanced between mice

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Psychiatry 29 , 30973105 (2024)

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