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68 Although the concentration of free copper in cells is almost negligible, it still has a potentially detrimental effect on cell membranes, proteins, and nucleic acids

Hg gas and its compounds are highly toxic and enter the body via respiratory inhalation, ingestion, and skin contact, causing systemic damage

The interplay between TLRs and PAMPs transmits chemical signals that trigger the process of pathogen engulfment and the secretion of pro-inflammatory cytokines that enhance local immune response some progress to viral pneumonia, multi-organs failure, or cytokine storm [14]

Glutathione is the predominant thiol compound in very many cells, both prokaryotes and eukaryotes, where its total intracellular concentration is usually in the range 0.5 to 12 mM

Anal Chem 90:69756983

The animals were kept in a 12-hour light/dark cycle and maintained on standard rat laboratory chow and tap water ad libitum