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These detrimental effects are mediated by complex mechanisms, including direct hepatotoxicity, oxidative stress, immune dysregulation, oncogenic signaling, and systemic metabolic disturbances

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Without it, scientists cannot determine whether it is effective or safe in humans

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[DOI] [PMC free article] [PubMed] [Google Scholar] Bruschi S.A., West K.A., Crabb J.W., Gupta R.S., Stevens J.L