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[PubMed] [Google Scholar] 217.Kim YH, Park KH, Rho HM

The nuclear factor-kappa B (NF-B) pathway-critical for inflammationis hyperactivated in M1 macrophages, leading to sustained cytokine production (93, 94)

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The preliminary human phase I trial has shown favorable pharmacokinetics and safety profiles, indicating the potential of HRX215 to prevent liver failure associated with small-for-size syndrome after extensive liver resection