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With the latest incidence data, primary carnitine deficiency turns out as one of the most common inherited metabolic disease in Chinese (the incidence as high as 1 in 10,000) and up to a thousand patients have been diagnosed and treated in the Greater China region during the last 20 years

Depression: disruption of synapse number and function Disruption of complex mood related circuitry has been implicated in depression (Box 3), but among the findings of altered brain structure and function in depression, the most consistent is reduced volume of the Prefrontal cortext (PFC) and hippocampus 7,8

In another similar report, Sagwal et al