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PPAR is able to upregulate the expression of almost all genes involved in the carnitine shuttle mechanism (e.g., CPT1, CPT2, CACT and CrAT) [193, 194]

A CT scan of the head with contrast revealed no intraparenchymal metastases

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The absence of a pathologic nodal study involving sentinel nodes in the case of infiltrating melanoma could be a factor in poor prognosis, as happened with the sole reported case (case 3), which presented recurrence at the nodal level after 12 months with specific survival of 38 months

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