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doi: 10.1038/sj.onc.1202791

It tends to happen with inherited MHC-II types certain HLA types

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Although the side effects are generally low, it is typically high in sodium and it may cause weight gain, kidney damage and joint pain

J Thorac Oncol 14(7):1172-1183, 2019

the dose was subsequently increased to 5 mg/day
