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Yamatani K, Tabe Y, Saito K, Yang H, Murakami-Tonami Y, Suzuki K, Zhang W, Kinjo S, Ikeo K, Mogushi K, Hosoya M, Yamaguchi S, Harada H, Miida T, Shah NP, Konopleva MY, Hayashizaki Y, Andreeff M

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Small but sufficient amounts of 2,3-BPG are found in most cells, with the notable exception of red blood cells, where it is synthesized through the RapoportLuebering shunt

Epitalon activates telomerase gene expression, triggering a cascade of cellular responses

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The longer these free radicals have to wreak havoc in the cell, the more damage they do to the cells genetic material