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Nat Med 25(5):716729 Sukri A, Lopes BS, Hanafiah A (2021) The Emergence of multidrug-resistant Helicobacter pylori in Southeast Asia: a systematic review on the trends and intervention strategies using antimicrobial peptides

doi: 10.3390/antiox1005072

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However, high ROS accumulation leads to oxidative damage of cell components and cell death (57)

Pro-inflammatory cytokines, prostaglandin E2, nitrite production, inducible NOS (iNOS) and cyclooxygenase-2 expression, NF-B activation, and Nrf2 nuclear translocation and HO-1 expression/activity were all suppressed during this decrease

As previously discussed, the efficacy of previous modalities might be limited by associated adverse events and complications