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The oncology drug elesclomol selectively transports copper to the mitochondria to induce oxidative stress in cancer cells

A role for the extracellular signal-regulated kinase signal pathway in depressive-like behavior

126,127,158 Consequently, HK-R lacks the porin-binding domain that mediates HK-I binding to mitochondria

You add 2 mL of water (which is 200 units on the syringe)

However, this model might be very useful to investigate the early stage of melanoma to find a potential therapy and limit the progression to the advanced stage

doi: 10.3389/fpls.2023.1126567 Received 18 December 2022 Accepted 06 February 2023 Published 02 March 2023 Volume 14 - 2023 Edited by Vikas Srivastava, Central University of Jammu, India Reviewed by Danial Hassani, East China Normal University, China