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Methods Adults with previously untreated, high-risk HER2-positive eBC (T3 or node-positive [N13], including inflammatory disease) were randomized 1:1:1 to: T-DXd-THP: T-DXd 5.4 mg/kg every 3 weeks 4 cycles THP 4 cycles (n=321) ddAC-THP: Doxorubicin + cyclophosphamide every 2 weeks 4 cycles THP 4 cycles (n=320) T-DXd alone: 5.4 mg/kg every 3 weeks 8 cycles (n=286) The primary endpoint was pathologic complete response (pCR

Affinity, USA), anti-TNF- (17590-1-AP, 1:500

Finally, the significance of this dataset extends beyond academic research

[DOI] [PubMed] [Google Scholar] 6.Knig D, Kohl J, Jerger S, Centner C: Potential relevance of bioactive peptides in sports nutrition

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Elucidating drugtarget interactions, signaling pathway regulation, and biological effect generation enables precise characterization of drug action modes and therapeutic outcomes, providing a scientific foundation for optimized disease management