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doi: 10.18632/aging.205253 241 PanXKongXFengZJinZWangMLuHet al

J Cardiovasc Thorac Res

Patel S, Alvarez-Guaita A, Melvin A, Rimmington D, Dattilo A, Miedzybrodzka EL, Cimino I, Maurin AC, Roberts GP, Meek CL, Virtue S, Sparks LM, Parsons SA, Redman LM, Bray GA, Liou AP, Woods RM, Parry SA, Jeppesen PB, Kolnes AJ, Harding HP, Ron D, Vidal-Puig A, Reimann F, Gribble FM, Hulston CJ, Farooqi IS, Fafournoux P, Smith SR, Jensen J, Breen D, Wu Z, Zhang BB, Coll AP, Savage DB, ORahilly S (2019) GDF15 provides an endocrine signal of nutritional stress in mice and humans

doi: 10.1152/physrev.00045.2019 51 WoolfCJ

MTHFR is located on chromosome 1p36.22 and spans ~20.3 kb, comprising 12 exons in the human genome
