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CD70 on nasopharyngeal carcinoma cells binds to CD27 on nave CD4 + T cells, driving differentiation to Tregs and their activation

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doi: 10.1128/MCB.00099-20 129 AlvarezMESavourASzabadosL

The oral formulation's convenience advantage over injectable semaglutide would be even more pronounced in pediatric populations, potentially making orforglipron the preferred first-line pharmacological option for adolescent obesity if efficacy and safety data support its use