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However, the inhibitory effect of DHODH on ferroptosis is relatively subtle
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3,5-Bis-trifluoromethylphenyl-substituted BPM29 downregulates PKM2 expression in BV2 microglia, inhibiting NLRP3 inflammasome formation and promoting an anti-inflammatory phenotype, suggesting its potential for treating demyelinating diseases [8]
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[DOI] [PMC free article] [PubMed] [Google Scholar] 188.Pillai R, LeBoeuf SE, Hao Y, New C, Blum JLE, Rashidfarrokhi A, et al
10.1093/ndt/16.7.1483 Guillaume CP, Stolk L, Dejagere TF, Kooman JP: Successful use of hemodialysis in acute valproic acid intoxication
